文献类型：会议

作　　者：胡明慧 李岩 任欢

作者单位：哈尔滨医科大学基础医学院免疫学教研室

会议文献：第八届全国免疫学学术大会论文集

会议名称：第八届全国免疫学学术大会

会议日期：20121018

会议地点：中国重庆

主办单位：中国免疫学会（Chinese Society for Immunology）

出版日期：20121018

学会名称：中国免疫学会

语　　种：中文

摘　　要：<正>Background interleukin-17(IL-17)were previously defined as a pro-inflammatory cytokine and shown to play a vital role in the development of autoimmune diseases.Purpose This study aimed to investigate the potential role of IL-17 in neuronal protection in neuroinflammation and in homeostasis of autoimmune diseases.Methods Lewis rats were immunized with interphotoreceptor retinoid-binding protein(I RBP)to induce a monophasic EAU.relative expression of the multiple effector T cell-associated molecules and neurotrophic factors was analyzed by real time RT-PCR;the production of IL-17 in retina was examined by immunohis-

关 键 词：Neuroprotection effect of IL-17 in an autoimmune disease mediated neuroinflammation  

分 类 号：R593.2[临床医学类]