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脾胃湿热证与水通道蛋白4基因表达的关系
lationship between Slpeen-stomach Damp-heat Syndrome and Gene Expression of Aquaporin 4</p> <span class="by"></span>
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<p class='class'><strong>文献类型：</strong>期刊文章</p><p class='author'><strong>作 者：</strong><b class='type_ico_id'></b>周正[1] <b class='type_ico_id'></b>劳绍贤[1] <b class='type_ico_id'></b>黄志新[1] <b class='type_ico_id'></b>黄烈平[1] <b class='type_ico_id'></b>张向菊[2] <b class='type_ico_id'></b>胡斌[3] </p><p class='en'> </p><p class='organ'><strong>机构地区：</strong><b class='type_ico_id'></b>[1]广州中医药大学第一附属医院,广州510405 <b class='type_ico_id'></b>[2]广州中医药大学第二临床医学院 <b class='type_ico_id'></b>[3]中山大学达安基因诊断中心 </p><p class='from'><strong>出 处：</strong><a target='_blank'><b class='type_ico_id'></b></a>《中国中西医结合消化杂志》</p><p class='fund'><strong>基 金：</strong>国家自然科学基金资助项目(No.30271572)</p><p class='class'><strong>年 份：</strong>2004</p><p class='class'><strong>卷 号：</strong>12</p><p class='class'><strong>期 号：</strong>2</p><p class='class'><strong>起止页码：</strong>71-73</p><p class='class'><strong>语 种：</strong>中文</p><p class='class'><strong>收录情况：</strong>CAS、IC、RCCSE、ZGKJHX、普通刊</p><p class='abstrack'><strong>摘 要：</strong>目的:从水液代谢来研究脾胃湿热证与水通道蛋白4(AQP4)基因的关系。方法:慢性浅表性胃炎患者25例,其中脾胃湿热证15例.脾气虚证10例,另10例健康志愿者为对照。荧光定量PCR法检测AQP4在各组胃粘膜组织中的mRNA表达量。结果:脾胃湿热证组胃粘膜组织中AQP4 mRNA表达量为(10.00±8.83)×106cps／ml,显著高于脾气虚证组(1.28±2.93)×106cps／ml(P<0.01);而脾气虚证组则明显低于对照组[(2.99±3.33)×106cps／ml,P<0.05].结论.AQP4基因表达的异常可能是脾胃湿热证的发生机制之一。</p><p class='subject'><strong>关 键 词：</strong><b class='type_ico_id'></b>脾胃湿热证 <b class='type_ico_id'></b>水通道蛋白4 <b class='type_ico_id'></b>基因表达 <b class='type_ico_id'></b>慢性浅表性胃炎 <b class='type_ico_id'></b>荧光定量PCR法 诊断标准 </p><p class='class'><strong>分 类 号：</strong>R256.3] </p>
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