文献类型：期刊文章

作　　者：张利东[1] 徐建国[1] 王国林[2] 马虹[3] 闵苏[4] 缪长虹[5] 左明章[6] 杨建军[7] 刘克玄[8] 袁红斌[9] 鲍红光[10] 顾连兵[11] 孙杰[12]

Zhang Lidong;Xu Jianguo;Wang Guolin;Ma Hong;Min Su;Miao Changhong;Zuo Mingzhang;Yang Jianjun;Liu Kexuan;Yuan Hongbin;Bao Hongguang;Gu Lianbing;Sun Jie(Department of Anesthesiology,General Hospital of Eastern Theater Command,PLA,Nanjing 210002,China;Department of Anesthesiology,Tianjin Medical University General Hospital,Tianjin 300052,China;Department of Anesthesiology,the First Hospital of China Medical University,Shenyang 110001,China;Department of Anesthesiology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China;Department of Anesthesiology,Fudan University Shanghai Cancer Center,Shanghai 200032,China;Department of Anesthesiology,Beijing Hospital,Beijing 100730,China;Department of Anesthesia and Perioperative Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450002,China;Department of Anesthesiology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Department of Anesthesiology,Shanghai Changzheng Hospital,Shanghai 200071,China;Department of Anesthesiology and Pain,Nanjing First Hospital Nanjing First Hospital,Nanjing Medical University,Nanjing 210006,China;Department of Anesthesiology,Jiangsu Cancer Hospital Jiangsu Institute of Cancer Research Nanjing Medical University Affiliated Cancer Hospital,Nanjing 210009,China;Department of Anesthesiology,Jiangsu Province Hospital the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]东部战区总医院麻醉科,南京210002 [2]天津医科大学总医院麻醉科,300052 [3]中国医科大学附属第一医院麻醉科,沈阳110001 [4]重庆医科大学附属第一医院麻醉科,400016 [5]复旦大学附属肿瘤医院麻醉科,上海200032 [6]北京医院麻醉科,100730 [7]郑州大学第一附属医院麻醉与围术期医学部,450002 [8]南方医科大学南方医院麻醉科,广州510515 [9]上海长征医院麻醉科,200071 [10]南京市第一医院南京医科大学附属南京医院麻醉疼痛科,210006 [11]江苏省肿瘤医院江苏省肿瘤防治研究所南京医科大学附属肿瘤医院麻醉科,210009 [12]江苏省人民医院南京医科大学附属第一医院麻醉科,210029

出　　处：《中华麻醉学杂志》

年　　份：2020

卷　　号：40

期　　号：6

起止页码：641-645

语　　种：中文

收录情况：BDHX、BDHX2017、CAS、CSCD、CSCD_E2019_2020、JST、ZGKJHX、核心刊

摘　　要：地佐辛是术后镇痛常用药物,可单独用于术后轻、中度疼痛的镇痛,也可与非甾体类抗炎药(NSAIDs)、强效阿片类药物等复合用于术后重度疼痛的镇痛;该药还可作为外周神经阻滞、局部浸润麻醉镇痛不足的补救用药。复合用药时,因为镇痛药剂量降低以及药物对各种类型阿片受体的作用不同,呼吸抑制和成瘾等副作用较少,是突出的优点。该药虽广泛应用于术后镇痛,甚至用于术中镇痛,但仍缺乏建立在循证医学基础上的评价,仍需进一步严格对照研究。

关 键 词：局部浸润麻醉 地佐辛 呼吸抑制  循证医学  术后镇痛  外周神经阻滞 中度疼痛 阿片受体

分 类 号：R971.2]