文献类型：期刊文章

作　　者：刘毅[1,2,3] 王伟[1,2,4] 赵玉英[1,2] 陈虎彪[5] 梁鸿[1,2] 张庆英[1,2]

机构地区：[1]北京大学医学部药学院 天然药物及仿生药物国家重点实验室 [2]天然药物学系,北京100191 [3]中国食品药品检定研究院,北京100050 [4]清华大学生命科学院,北京100084 [5]香港浸会大学中药学院,香港999077

出　　处：《Journal of Chinese Pharmaceutical Sciences》

基　　金：Quality Standards for Chinese Medicines of Chinese Pharmacopeia 2010 edition(Grant No.YZ-029);National Natural Science Foundation of China(Grant No.21372015)

年　　份：2015

卷　　号：24

期　　号：10

起止页码：654-659

语　　种：中文

收录情况：CAB、CAS、CSCD、CSCD2015_2016、DOAJ、EMBASE、IC、JST、SCOPUS、ZGKJHX、普通刊

摘　　要：The root of Hedysarum multijugum（RHM） is recorded as a folk herbal medicine in China and is sometimes used as a substitute for Hedysari Radix, which is a famous traditional Chinese medicine derived from the roots of Hedysarum polybotrys. In the present study, a sensible, reliable, and reproducible HPLC-DAD fingerprint analysis method for RHM was developed and then subsequently applied to analyze RHM samples from different origins. The chemical constituents of the RHM samples were generally consistent, although it was slightly affected by the local environment of the plant. In addition, the chemical constituency of RHM was shown to be significantly different from that of Hedysari Radix, suggesting that RHM is not suitable as a substitute for Hedysari Radix, at least from the chemical point of view.

关 键 词：Hedysarum multijugum  HEDYSARUM HPLC fingerprint  Quality analysis  Species identification  

分 类 号：R284[中药学类]