文献类型：期刊文章

作　　者：李青山[1] 黄计军[1] 杨频[2] 王瑞卿[3]

机构地区：[1]山西医科大学药学系,太原030001 [2]山西大学分子所,太原030001 [3]北京医科大学天然药物及仿生药物国家重点实验室,北京100083

出　　处：《中国药物化学杂志》

基　　金：国家科技部重点资助项目!(No.9690106038);国家自然科学基金!资助项目(No.39900185)

年　　份：1999

卷　　号：9

期　　号：4

起止页码：297-302

语　　种：中文

收录情况：AJ、CAS、CSCD、CSCD_E2011_2012、JST、ZGKJHX、普通刊

摘　　要：Four new diorganotin complexes were synthesized and characterized by IR and 1H NMR.Their in vitro antitumor activities against a series of human tumor cell lines such as P 388 tumor cells were tested.The results showed that the complexes mainly exhibited strong antitumor activities against P 388 ,but presented no activities against other tumor cell lines.The structure activity relationships were discussed.

关 键 词：有机锡化合物 合成  抗癌活性

分 类 号：TQ463.6[化工与制药类] R979.1]