文献类型：期刊文章

作　　者：熊伟[1] 汤波[1] 刘德蓉[1] 贾云[1] 王孝科[1] 袁茂林[2] 李贤均[2]

机构地区：[1]重庆科技学院化学化工学院,重庆400050 [2]四川大学化学学院有机金属络合催化研究所、绿色化学及技术教育部重点实验室,四川成都610064

出　　处：《化学研究与应用》

年　　份：2008

卷　　号：20

期　　号：8

起止页码：1050-1055

语　　种：中文

收录情况：BDHX、BDHX2004、CAS、CSCD、CSCD2011_2012、JST、RSC、ZGKJHX、核心刊

摘　　要：The RuCl2(PPh3)3/γ-Al2O3 catalyst modified by chiral reagent(1S,2S)-(-)-1,2-diphenyl-1,2-ethylenediamine((1S,2S)-DPEN) was investigated for the asymmetric hydrogenation of acetophenone and its derivatives.At the optimized reaction conditions,85% conversion of acetophenone and 82%e.e.of(R)–α-phenyl ethanol were achieved over RuCl2(PPh3)3/γ-Al2O3 catalyst modified by(1S,2S)-DPEN.Furthermore,the results indicated that there was a synergistic effect between(1S,2S)-DPEN and KOH,which significantly accelerated the reaction rate and enantioselectivity.

关 键 词：钌膦配合物 苯乙酮 不对称加氢 对映选择性

分 类 号：O634.41]