文献类型：期刊文章

作　　者：龚华俊[1] 杨小平[1] 陈国强[2] 刘太奇[3] 张淑敏[3] 邓旭亮[4] 胡晓阳[4]

机构地区：[1]北京化工大学北京市新型高分子材料加工重点实验室,北京100029 [2]清华大学第二附属医院,北京100039 [3]北京石油化工学院材料化工学院,北京102617 [4]北京大学口腔医学院,北京100081

出　　处：《高分子学报》

基　　金：国家 8 63项目 (项目号 2 0 0 3AA3 0 2 2 2 0 ) ;国家自然科学基金 (基金号 3 0 47190 7);归国人员人事部科研专项基金 [基金号国人发 (2 0 0 3 ) 90号 ]资助项目

年　　份：2005

卷　　号：15

期　　号：2

起止页码：297-300

语　　种：中文

收录情况：AJ、BDHX、BDHX2004、CAS、CSCD、CSCD2011_2012、IC、JST、PL、RCCSE、SCI(收录号：WOS:000228686200029)、SCI-EXPANDED(收录号：WOS:000228686200029)、SCIE、SCOPUS、WOS、ZGKJHX、核心刊

摘　　要：PLA/MWNT/HA hybrid nanofibers were prepared via electrospinning technology.Multi walled carbon nanotube (MWNT) were first treated by anodic oxidation,which resulted in various functional groups such as C—O,CO and O—CO on the surface of oxidized MWNT.Then the MWNT/hydroxyapatite (HA) nano composites (MWNT content 3?wt%) were in situ synthesized by wet method with the help of ultrasonic treatment.Because of the strong interaction between the functional groups on the surface of MWNT and Ca 2+ in HA,the obtained HA nano particles were deposited onto the surface of oxidized MWNT.The as received MWNT/HA nano composites with excellent biocompatibility and osteoinduction were introduced into a bioabsorbable polymer,polylactide (PLA),and the PLA/MWNT/HA hybrid nanofibers were electrospun through a double solvent method under the voltage of 18 kV and the capillary to target distance was 4?cm.The structure and morphology of hybrid nanofibers were characterized by SEM.Because of the nanoscaled diameters,microscaled interconnected pores and suitable surface chemistry,the hybrid nanofibers would match the requirements of ideal bone tissue engineering scaffold and may be a potential material for preparing bone tissue engineering scaffold.

关 键 词：多壁碳纳米管 羟基磷灰石 纳米纤维  聚乳酸 纺丝法  杂化  制备  聚合物溶液  加工技术  纤维直径  有效方法  纳米尺寸 强电场 电纺丝 数量级  长纤维  喷射  

分 类 号：TQ340]