期刊文章详细信息
CPT-11联合5-FU/FA方案治疗局部晚期或转移性结直肠癌的临床研究
inical study of CPT-11 combined with 5-FU/FA policy in patients with advanced or metastatic colorectal cancer</p> <span class="by"></span>
</h1>
<p>
</p>
<p class="from">
</p>
<p id="webbody_ArticlesDetailSummary1_link" class="link">
<a href='javascript:void(0)' onclick="Addcollection(this)">
<img alt='收藏' src='/images_new/obj_favior.gif' /></a>
<span id="bdshare" class="bdshare_t bds_tools get-codes-bdshare baidufx"><span><span
class="bds_more" style="display: block; width: 65px; height: 23px; background: url(/Template/t5/images/share.gif) no-repeat!important; padding-top: 0; padding-left: 10px;"></span></span></span>
<script>
function Addcollection(obj) {
var objecttype = '1';
var objectid = '1001083401';
var name = 'CPT-11联合5-FU/FA方案治疗局部晚期或转移性结直肠癌的临床研究';
var globalOrganId = '3233';
if (!checkLogin(globalOrganId)) {
location.href = "/" + globalOrganId + "/login.aspx?returnUrl=" + encodeURIComponent(window.location);
return;
}
//提交删除
$.ajax({
type: "get",
url: "/ajax/UserCollectionHandler.ashx",
data: { ObjectType: objecttype, ObjectID: objectid, Name: name, globalOrganId: globalOrganId, ts: new Date().getTime() },
dataType: 'text',
async: false,
success: function (msg) {
alert(msg);
}
});
}
</script>
</p>
<div class="collect" style="display: none">
<h5>我的收藏</h5>
<div class="cnt">
<p>
名 称：<input type="text" name="collTitle" id="collSumTitle" />
</p>
<p>
注 释：<input type="text" name="collRemark" id="collSumRemark" />
</p>
<p style="text-align: center;">
<a href="javascript:void(0)" onclick="g_collectSumOk();">
<img width="65" height="17" src="/Template/t5/images/collect_ok.png" alt="完成" /></a>
<a href="javascript:void(0)" onclick="g_collectSumCancel();">
<img width="65" height="17" src="/Template/t5/images/collect_no.png" alt="取消" /></a>
</p>
</div>
</div>
</div>
<script type="text/javascript" id="bdshare_js" data="type=tools&uid=0"></script>
<script type="text/javascript" id="bdshell_js"></script>
<script type="text/javascript">
/**加载百度分享*/
$(function () {
document.getElementById("bdshell_js").src = "http://bdimg.share.baidu.com/static/js/shell_v2.js?cdnversion=" + Math.ceil(new Date() / 3600000);
});
function hidesavepad() {
$("#changyanid,#changyanbg").hide();
}
function showcy() {
$("#changyanbg,#changyanid").show();
}
</script>
<div class="article_detail ">
<p class='class'><strong>文献类型：</strong>期刊文章</p><p class='author'><strong>作 者：</strong><b class='type_ico_id'></b>樊青霞[1] <b class='type_ico_id'></b>吴欣爱[1] <b class='type_ico_id'></b>王留兴[1] <b class='type_ico_id'></b>王瑞林[1] <b class='type_ico_id'></b>范魁生[1] <b class='type_ico_id'></b>许莉[1] <b class='type_ico_id'></b>路平[2] <b class='type_ico_id'></b>刘湘宁[3] </p><p class='en'> </p><p class='organ'><strong>机构地区：</strong><b class='type_ico_id'></b>[1]郑州大学第一附属医院肿瘤科,郑州450052 <b class='type_ico_id'></b>[2]新乡医学院附属医院肿瘤科 <b class='type_ico_id'></b>[3]中国人民解放军153医院外科 </p><p class='from'><strong>出 处：</strong><a target='_blank'><b class='type_ico_id'></b></a>《癌症进展》</p><p class='class'><strong>年 份：</strong>2004</p><p class='class'><strong>卷 号：</strong>2</p><p class='class'><strong>期 号：</strong>6</p><p class='class'><strong>起止页码：</strong>478-481</p><p class='class'><strong>语 种：</strong>中文</p><p class='class'><strong>收录情况：</strong>JST、ZGKJHX、普通刊</p><p class='abstrack'><strong>摘 要：</strong>目的 评价CPT-11(开普拓)联合5-FU／FA治疗局部晚期或转移性结直肠癌的临床疗效及不良反应。方法 符合收治标准者19例,可评价疗效者17例,入组Arm A方案8例,Arm B方案9例,ArmA方案:CP-11 270mg/m2静滴d1;FA200mg／m2,5-FU 425mg／m2分别静滴,均d1-5,每3周重复,两次CPT-11(6周)评价疗效。ArmB方案:CPT-11 180mg/m2静滴d1,LA200mg/m2,静滴d1-2,5-FU 400mg／m2静推,然后5-FU 600mg／m2,d1-2,每2周重复,应用3次CPT-11(6周)为一个周期。结果 17例患者,CR 1例,PR 5例,SD 9例,PD 2例,总缓解率35％,稳定率52.9％,中位缓解时间7.5个月,中位稳定时间5个月。主要剂量限制毒性为迟发性腹泻及中性粒细胞减少。结论 CPT-11联合5-FU／FA两种方案治疗局部晚期或转移性结直肠癌有较高的疾病缓解率和稳定率,主要剂量限制毒性为迟发性腹泻及中性粒细胞减少。</p><p class='subject'><strong>关 键 词：</strong><b class='type_ico_id'></b>结直肠癌 <b class='type_ico_id'></b>CPT-11 临床研究 <b class='type_ico_id'></b>化疗 </p><p class='class'><strong>分 类 号：</strong>R735.3+4] </p>
</div>
<div id="webbody_wzxg" name="wzxg" class="article_graph">
<object width="695" height="250" classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000"
id="FlashID">
<param value="/flash/relation.swf" name="movie">
<param value="high" name="quality">
<param value="opaque" name="wmode">
<param value="6.0.65.0" name="swfversion">
<param value="dataUrl=/Template/t5/ajax/Article_Relative_Graph.ashx?id=1001083401_3233" name="flashVars">
<embed width="695" height="250" src="/flash/relation.swf" type="application/x-shockwave-flash"
quality="high" wmode="opaque" flashvars="dataUrl=/Template/t5/ajax/Article_Relative_Graph.ashx?id=1001083401_3233">
</embed>
</object>
</div>
<div class="article_relate_list">
<div>
<h2 name="ckwx" id="ckwx">
参考文献：</h2>
<div id="listckwx">
<p class='submit'>
<img src='/images_new/loading.gif' width='16' height='16' />
正在载入数据...</p>
</div>
</div>
<div>
<h2 name="2jckwx" id="2jckwx">
二级参考文献：</h2>
<div id="list2jckwx">
<p class='submit'>
<img src='/images_new/loading.gif' width='16' height='16' />
正在载入数据...</p>
</div>
</div>
<div>
<h2 name="ohwx" id="ohwx">
耦合文献：</h2>
<div id="listohwx">
<p class='submit'>
<img src='/images_new/loading.gif' width='16' height='16' />
正在载入数据...</p>
</div>
</div>
<div>
<h2 name="yzwx" id="yzwx">
引证文献：</h2>
<div id="listyzwx">
<p class='submit'>
<img src='/images_new/loading.gif' width='16' height='16' />
正在载入数据...</p>
</div>
</div>
<div>
<h2 name="2jyzwx" id="2jyzwx">
二级引证文献：</h2>
<div id="list2jyzwx">
<p class='submit'>
<img src='/images_new/loading.gif' width='16' height='16' />
正在载入数据...</p>
</div>
</div>
<div>
<h2 name="tbywx" id="tbywx">
同被引文献：</h2>
<div id="listtbywx">
<p class='submit'>
<img src='/images_new/loading.gif' width='16' height='16' />
正在载入数据...</p>
</div>
</div>
</div>
</div>
<div class="r">
</div>
<div class="clear">
</div>
</div>
</div>
<div class="vlink_layer" style="display: none">
<div class="vlink">
<img src="/template/t1/images/loading2.gif" width="64" height="64">
<span style="font-size:22px;vertical-align:middle;margin-left:20px;">正在为您导引到下载地址...</span>
</div>
<div id="vlink" style="display: none"></div>
</div>
<script type="text/javascript" src="/Template/t5/js/article_relative.min.js"></script>
<script type="text/javascript" src="/js/articlevlink.min.js"></script>
<div class="foot">
<div class="inner">
<p style="text-align: center;">
版权所有©重庆科技学院
<script type="text/javascript">
document.write("2001-" + new Date().getFullYear());
</script>
重庆维普资讯有限公司 <a target="_blank" href="https://beian.miit.gov.cn/#/Integrated/recordQuery">渝B2-20050021-7</a><br />
<a target="_blank" href="http://www.beian.gov.cn/portal/registerSystemInfo?recordcode=50019002500408"><img style="position:relative; top:5px; margin-right:3px;" src="/images_new/ghs.png" /><span style="color:inherit;">渝公网安备 50019002500408号</span></a> 违法和不良信息举报中心
<p>
</div>
</div>
<a id="backtop" style="display: none" href="javascript:void(0)" title="返回顶部"></a>
<script type="text/javascript">
$(function () {
$('#backtop').hover(function () {
$(this).css({ opacity: 1 });
},
function () {
$(this).css({ opacity: 0.8 });
});
$('#backtop').click(function () {
$('html,body').animate({ scrollTop: 0 }, 100);
});
$(window).scroll(function () {
var scroH = document.documentElement.scrollTop + document.body.scrollTop;
if (scroH > $('.head').height()) {
$('#backtop').show();
} else {
$('#backtop').hide();
}
});
});
/**google代码*/
$(function () {
// (function (i, s, o, g, r, a, m) {
// i['GoogleAnalyticsObject'] = r; i[r] = i[r] || function () {
// (i[r].q = i[r].q || []).push(arguments);
// }, i[r].l = 1 * new Date(); a = s.createElement(o),
//m = s.getElementsByTagName(o)[0]; a.async = 1; a.src = g;
// m.parentNode.insertBefore(a, m);
// })(window, document, 'script', '//www.google-analytics.com/analytics.js', 'ga');
// ga('create', 'UA-2219013-35', 'cqvip.com');
// ga('send', 'pageview');
});
</script>
<!--[if IE 6]>
<script type="text/javascript" src="/js/lib/DD_belatedPNG.min.js"></script>
<script type="text/javascript">
$(document).ready(function () {
/**png图片修正*/
DD_belatedPNG.fix('.logo, .logo a img, .ico_login, .ico_reg, .ico_help, .head_search .search, .head_search .search_guid a, .head_search .search_relative .relative_intro, .head_search .search_relative .relative_op a, .top, .top h1, .user_info .hide tt, li, .search_list .num .t, .search_report h2 em, .search_report, .article_search_list .num .t, .m_op .cl img, .graph_list .sort img, .guid .class .cn1 span, .guid .class .cn2 span, .graph_top h3, .head_nav li a');
});
</script>
<![endif]-->
<script type="text/javascript">
$(function () {
var urlPath = location.href;
var request = g_getUrlParms();
//当检索条件不为空时，为检索框赋值
if (!request.q) {
$("#artcleSearchCondtion").val("");
} else {
var json1 = JSON.parse(request["q"]);
if (!request.invokemethod&&json1.ajaxKeys && urlPath && urlPath.indexOf("articles.aspx")!=-1) {
$("#artcleSearchCondtion").val(decodeURI(json1.ajaxKeys).replace(/\+/g, " "));
$("#dropSearchFieldName").find("option[showField='"+json1.customShowCondition.split('=')[0]+"']").prop("selected","selected");
} else {
$("#artcleSearchCondtion").val("");
}
}
$("#dropSearchFieldName").easySelectBox();
$("#artcleSearchCondtion").keydown(function (event) {
var e = $.event.fix(event);
if (e.keyCode == 13) {
$("#artcleSearchBtn").click();
return false;
}
});
$("#artcleSearchBtn").click(function () {
var fieldValue = $("#artcleSearchCondtion").val();
if (!fieldValue) {
alert("检索内容不能为空！");
} else {
var condition = {};
var fieldName= $("#dropSearchFieldName").val();
var tempField = fieldName.split("@");
var tempFieldName = tempField[0].split("|");
if (tempFieldName[0] == "multiple") //期刊题名或关键词检索条件拼接
{
condition.customRules = "(" + getSearchRules("title_c", fieldValue) + " OR " + getSearchRules("title_e", fieldValue) + " OR " + getSearchRules("keyword_e", fieldValue) + " OR " + getSearchRules("keyword_c", fieldValue) + " OR " + getSearchRules("subject_text", fieldValue) + ")";
}
else {
if (tempFieldName.length == 1) { //当检索规则只含有一个字段
condition.customRules = getSearchRules(tempFieldName, fieldValue);
} else {
var flag = true;
var customStr = "(";
for (var i = 0; i < tempFieldName.length; i++) { //按检索规则字段个数，循环拼接检索条件，此处各字段间为OR关系
if (flag) {
customStr += getSearchRules(tempFieldName[i], fieldValue);
} else {
customStr += " OR " + getSearchRules(tempFieldName[i], fieldValue);
}
flag = false;
}
customStr += ")";
condition.customRules = customStr;
}
}
condition.customShowCondition = tempField[1] + "=" + fieldValue;
condition.ajaxKeys = fieldValue;
location.href = "/3233/articles.aspx?q=" + encodeURIComponent(JSON.stringify(condition));
if (window.event)
window.event.returnValue = false; //ie6fix
}
});
});
/**返回格式化的搜索规则*/
function getSearchRules(fieldName, fieldValue) {
var returnValue = "";
if (fieldName == "worknumber") {
$.ajax({
type: "get",
url: "/ajax/WriterIdByWorkNumber.ashx",
data: { "organid": "" + $('#hidGlobalOrganID').val() + "", "number": "" + fieldValue + "", "_t": new Date },
dataType: 'text',
async: false,
success: function (msg) {
if (!msg) {
msg = "0";
}
returnValue = "({0}:\"{1}\")".format("writerids_s", msg);
}
});
} else {
returnValue = fieldName == "ALL" ? "({0}:\"{1}\")".format(fieldName, fieldValue.toLowerCase()) : "({0}:\"{1}\")".format(fieldName, fieldValue.toLowerCase());
}
return returnValue;
}
</script>
<div class="layer_bg" style="display: none" id="serLayerBg">
</div>
<div class="advance_layer" style="display: none; top: 150px;" id="serAdvanceLayer">
<form>
<div class="advance">
<h6>
<tt class="close" onclick=" g_HideAdvanceSearch(); ">
<img alt="x" src="/Template/t5/images/advance-close.gif"></tt>
</h6>
<div class="cnt" id="cnt1">
<div class="sinput_top">
<div class="sel">
<input type="hidden" id="hfldFieldNameArticles0" name="hfldFieldNameArticles" />
<select name="dropAdvanceSearchFieldName" style="display: none">
</select>
</div>
<div class="input">
<input type="text" name="txtSearchArticles" id="txtSearchArticles0" maxlength="50"/>
</div>
</div>
<div class="sinput">
<div class="s">
<input type="hidden" value=" AND | 与 " name="hfldRelationArticles" id="hfldRelationArticles1" />
<select name="dropAdvanceSearchLogic">
<option value=" AND | 与 ">与</option>
<option value=" OR | 或 ">或</option>
<option value="AND NOT | 非 ">非</option>
</select>
</div>
<div class="sel">
<input type="hidden" id="hfldFieldNameArticles1" name="hfldFieldNameArticles" />
<select name="dropAdvanceSearchFieldName" style="display: none">
</select>
</div>
<div class="input">
<input type="text" name="txtSearchArticles" id="txtSearchArticles1" maxlength="50"/>
</div>
</div>
<div class="sinput" style="display: none">
<div class="s">
<input type="hidden" value=" AND | 与 " name="hfldRelationArticles" id="hfldRelationArticles2" />
<select name="dropAdvanceSearchLogic">
<option value=" AND | 与 ">与</option>
<option value=" OR | 或 ">或</option>
<option value="AND NOT | 非 ">非</option>
</select>
</div>
<div class="sel">
<input type="hidden" id="hfldFieldNameArticles2" name="hfldFieldNameArticles" />
<select name="dropAdvanceSearchFieldName" style="display: none">
</select>
</div>
<div class="input">
<input type="text" name="txtSearchArticles" id="txtSearchArticles2" maxlength="50"/>
</div>
</div>
<div class="sinput" style="display: none">
<div class="s">
<input type="hidden" value=" AND | 与 " name="hfldRelationArticles" id="hfldRelationArticles3" />
<select name="dropAdvanceSearchLogic">
<option value=" AND | 与 ">与</option>
<option value=" OR | 或 ">或</option>
<option value="AND NOT | 非 ">非</option>
</select>
</div>
<div class="sel">
<input type="hidden" id="hfldFieldNameArticles3" name="hfldFieldNameArticles" />
<select name="dropAdvanceSearchFieldName" style="display: none">
</select>
</div>
<div class="input">
<input type="text" name="txtSearchArticles" id="txtSearchArticles3" maxlength="50"/>
</div>
</div>
<div class="sel_op">
<input type="button" class="add" /><input type="button" class="cut" />
</div>
<div class="filter">
<strong>时间：</strong>
<div class="t">
<input type="hidden" value="1989" id="hfldAdvanceStartYear" name="hfldAdvanceStartYear" />
<select name="dropAdvanceSearchYears" id="dropAdvanceSearchStartYears">
</select>
</div>
<span>-</span><div class="t">
<input type="hidden" value="2013" id="hfldAdvanceEndYear" name="hfldAdvanceEndYear" />
<select name="dropAdvanceSearchYears" id="dropAdvanceSearchEndYears">
</select>
</div>
</div>
<div class="filter">
</div>
<div class="submit">
<input type="button" onclick="g_AdvanceSearch(1);" value="确定" class="btn-green">
<input type="button" onclick="g_HideAdvanceSearch();" value="关闭" class="btn-gray">
</div>
</div>
</div>
</form>
</div>
<script type="text/javascript" src="/Template/t5/js/advancesearch.min.js"></script>
<script type="text/javascript">
$(function () {
var encodestr = $("#hifBaseLog").val().trim();
var BaseGch = "";
var BaseArticleId = "";
var BaseClass = "";
var BaseObjectType = 0;
var BaseObjectValue = "";
if (encodestr != "") {
var parames = encodestr.split(';');
BaseGch = parames[0];
BaseArticleId = parames[1];
BaseClass = parames[2];
BaseObjectType = parames[3];
BaseObjectValue = parames[4];
}
var obj = {};
obj.remark = "机构库站点访问记录-重庆科技学院";
obj.user_id = 0;
obj.user_ip_address = "18.119.112.17";
obj.user_group_id = 0;
obj.user_organ_id = 3233;
obj.site_id = 13;
if (BaseGch) {
obj.gch = BaseGch;
}
if (BaseArticleId) {
obj.article_id = BaseArticleId;
}
if (BaseClass) {
obj.full_class_ids = BaseClass;
}
if (BaseObjectType) {
obj.object_id = BaseObjectType;
}
if (BaseObjectValue) {
obj.object_value = BaseObjectValue;
}
loadScript("http://log.cqvip.com/VipCloud/Service/Log/js/analysis.js", function() { vipLog("view", obj,"LIBBEHAVIORANALYSIS"); });
});
</script>
</body>
</html>